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mercaptopurine

Synonyms

Noun

1. Purinethol

2. antimetabolite, immunosuppressant, immunosuppressive drug, immune suppressant drug

Usage
Influence of xanthine oxidase and inosine monophosphate dehydrogenase polymorphisms on 6-mercaptopurine treatment response in pediatric acute lymphoblastic leukemia - Nature
Allopurinol Add-on 6-Mercaptopurine Strategy Improves Efficacy and Reduces Toxicity in Pediatric Patients With Acute Lymphoblastic Leukemia - Wiley
Investigating adsorption of 5-fluorouracil and 6-mercaptopurine on icosahedral silver nanoparticles through DFT and TDDFT - Nature
Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study - Haematologica
Gertrude Elion: How one woman’s determination transformed cancer treatment - Blood Cancer UK
Call for public consultation: Target product profile for paediatric formulations of cyclophosphamide, etoposide, mercaptopurine, methotrexate, procarbazine and temozolomide - World Health Organization (WHO)
Impact of mercaptopurine schedule on hypoglycemia in leukemic children: randomized trial and risk factor analysis - Nature
Self-Reports Overestimate Mercaptopurine Intake in Childhood Acute Lymphoblastic Leukemia - The ASCO Post
Mercaptopurine and inflammatory bowel disease: the other thiopurine - SciELO España
Mercaptopurine in the Treatment of Steroid-Resistant Nephrotic Syndrome - The New England Journal of Medicine
Captopril and 6-mercaptopurine: Whose SH possesses higher antioxidant ability? - ScienceDirect.com
Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study - Haematologica
Mercaptopurine Oral Suspension for Acute Lymphoblastic Leukemia - The ASCO Post
Maintenance Treatment With Low-Dose Mercaptopurine in Combination With Allopurinol in Children With Acute Lymphoblastic Leukemia and Mercaptopurine-Induced Pancreatitis - Wiley Online Library
Maintenance therapy for acute lymphoblastic leukemia: basic science and clinical translations - Nature
Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation - Nature
Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy - Nature
Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death - Nature
Pharmacokinetic–pharmacodynamic modeling of maintenance therapy for childhood acute lymphoblastic leukemia - Nature
Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells - Nature
Allopurinol use during pediatric acute lymphoblastic leukemia maintenance therapy safely corrects skewed 6-mercaptopurine metabolism, improving inadequate myelosuppression and reducing gastrointestinal toxicity - Wiley Online Library
NUDT15 gene polymorphism related to mercaptopurine intolerance in Taiwan Chinese children with acute lymphoblastic leukemia - Nature
Stomach Pain Upon Stomach Pain: Medication-Induced Pancreatitis - Cureus
Gertrude B. Elion: The Woman Who Rewrote the Rules of Cancer Treatment - Oncodaily
Systemic Exposure to Mercaptopurine as a Prognostic Factor in Acute Lymphocytic Leukemia in Children - The New England Journal of Medicine
Your Good Health: Should medication for Crohn’s be changed due to cancer risk? - Times Colonist
Batch of Mercaptopurine tablets recalled due to ‘microbial contamination’ - thepharmacist.co.uk
Gold(I) N -heterocyclic carbene (NHC) complexes containing 6-mercaptopurine derivatives and their in vitro anticancer and anti-inflammatory effects - Wiley Online Library
Combination Therapy of Adult Acute Myelogenous Leukemia | NEJM - The New England Journal of Medicine
Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia - Nature
Distal toxic acral erythema and mucositis secondary to 6-mercaptopurine in a thiopurine methyltransferase “super shunter” - Wiley Online Library
High Dose Intensity Maintenance Therapy May Increase Risk of Toxicity, Relapse in Pediatric ALL - Hematology Advisor
DNA polymerase gamma variants and hepatotoxicity during maintenance therapy of childhood acute lymphoblastic leukemia: is there a causal relationship? - Nature
From niche to blockbuster: a greater role for allopurinol in maintenance treatment of acute lymphoblastic leukemia - Haematologica
PURIXAN® (mercaptopurine [6-MP] oral suspension) - Cancer Therapy Advisor
Interaction of 6MP with CT-DNA. - PLOS
FDA Warns of ICP Risk Associated With Thiopurine Use During Pregnancy - Gastroenterology & Endoscopy News
Liquid mercaptopurine licensed in Europe as Xaluprine - Hospital Pharmacy Europe
Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia | Scientific Reports - Nature
Loss of Nudt15 thiopurine detoxification increases direct DNA damage in hematopoietic stem cells - Nature
Bioequivalence study followed by model-informed dose optimization of a powder for oral suspension of 6-mercaptopurine - Wiley Online Library
Discovery lays the foundation to expand personalized chemotherapy for leukemia patients - St. Jude Children's Research Hospital
Cancer drug price hike company investigated - BBC
Hypersensitivity to azathioprine in a patient with Crohn's disease: a case report - SciELO España
A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group phase III randomized trial - Nature
Antimetabolite Therapy and Crohn’s Disease: Efficacy, Safety Examined - Medical Professionals Reference
Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia - Nature
Thiopurines: Factors influencing toxicity and response - ScienceDirect.com
Rare Pregnancy Problem Linked to Thiopurines, FDA Says - MedPage Today
Allopurinol Improves Safety and Efficacy in Paediatric Leukaemia Maintenance Therapy - EMJ
TMC and IDRS Labs introduce oral therapy for leukaemia in India - Pharmaceutical Technology
Anti-Inflammatory Drug Inhibits Resistant Triple-Negative Breast Cancer Cells - Technology Networks
FDA approval for Nova’s leukaemia drug - PMLiVE
Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine - Nature
Humira Gains Indication for the Treatment of Adults with Ulcerative Colitis - Medical Professionals Reference
Azathioprine-induced severe anemia potentiated by the concurrent use of allopurinol - CMAJ
TPMT and NUDT15 testing for thiopurine therapy: A major tertiary hospital experience and lessons learned - Frontiers
EC approves new Xaluprine formulation - Pharmafile
Gene variant linked to reduced thiopurine metabolism in African ancestry - Medical Xpress
Optimizing Use of Maintenance Therapy in ALL - OncLive
Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort - Nature
Improving pharmacovigilance in Europe: TPMT genotyping and phenotyping in the UK and Spain - Nature
Recent advances in the pharmacogenomics of thiopurine methyltransferase - Nature
Tata Hospital with Bangalore lab develop India’s first oral suspension for leukemia - The Times of India
Foreign Language Equivalents
Foreign Language Equivalents of 'mercaptopurine'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
mercaptipurine,   mrrcaptopurine,   mercaptopuribe,   mercaptopurime,   mrecaptopurine,   mercaptoourine,   nercaptopurine,   merrcaptopurine,   merca[topurine,   meecaptopurine,   meraptopurine,   mercaptpourine,   merccaptopurine,   mercaptopurinne,   mercaptopurune,   mercaptoopurine,   mercaptppurine,   mercaptourine,   meercaptopurine,   mercptopurine,   mercaptoppurine,   mercaptouprine,   merxaptopurine,   mercaptopuine,   mercaptpurine,   mercaptopurrine,   mercaptopurnie,   ercaptopurine,   mercaptopruine,   mercapto[urine,   mercaaptopurine,   mercaptopurinr,   mercapopurine,   mercaotopurine,   mercaptopyrine,   mervaptopurine,   mercaptopurien,   mercaptopirine,   mercaptopurinw,   mercapttopurine,   mercaptopurin,   mercaptoputine,   mercaptopurne,   mercaptopurone,   mercatopurine,   mercapropurine,   mercsptopurine,   metcaptopurine,   mercpatopurine,   mercaptopueine,   mercaptopuirne,   mmercaptopurine,   mercaptopurie,   meracptopurine,   ,ercaptopurine,   emrcaptopurine,   mercaptopurinee,   mercaptopuriine,   mrcaptopurine,   mercapotpurine,   mercaptoprine,   morcaptopurine,   mercaptopuurine,   mwrcaptopurine,   mecaptopurine,   mercapptopurine,   mercapyopurine,   mercatpopurine,   mecraptopurine
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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