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kinase

Synonyms

Noun

1. enzyme

Usage
Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing - Nature
Understanding Thymidine Kinase 2 Deficiency Before Disease-Modifying Therapy - NeurologyLive
Autophagolysosomal exocytosis inverts Src kinase onto the cell surface in cancer - Science | AAAS
ThalassaX Therapeutics Announces First Patient Dosed in U.S. Phase I Trial of CS231295, a Brain-Penetrant Aurora B Kinase Selective Inhibitor - Business Wire
Kinase atlas uncovers hidden layers of cell signaling regulation - St. Jude Children's Research Hospital
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies - Nature
The allosteric landscape of the Src kinase - Science | AAAS
MEK interactions tune RAF kinase sensitivity to conformation-selective inhibition - Nature
A universal polyphosphate kinase powers in vitro transcription - Nature
The emerging role of kinase fusion proteins in cereal immunity - Nature
Inhibitors supercharge kinase turnover through native proteolytic circuits - Nature
Activation mechanism of the full-length histidine kinase LvrB from pathogenic Leptospira - Nature
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis - Nature
Benchmarking EGF signaling pathway inference using phosphoproteomics and kinase-substrate interactions - Nature
Enhancing kinase-inhibitor activity and selectivity prediction through contrastive learning - Nature
Pharmacophore-driven kinase profiling applied to the PKIS2 chemogenomic dataset - Nature
Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling - Nature
Mutation type, tyrosine kinase function in normal cell and tyrosine kinase inhibitor activity in cancers | Scientific Reports - Nature
FDA approves 100th small-molecule kinase inhibitor - Nature
Exploring the conformational landscape of adenylate kinase and beyond with protein folding models - Nature
Kinase inhibitors shown to accelerate protein breakdown - Drug Target Review
Kinase inhibitors can be targeted protein degraders too - Chemical & Engineering News
Direct targeting and regulation of RNA polymerase II by cell signaling kinases - Science | AAAS
A web portal for exploring kinase-substrate interactions | npj Systems Biology and Applications - Nature
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature
Tandem kinase proteins across the plant kingdom - Nature
Molecular recording of cellular protein kinase activity with chemical labeling - Nature
Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N - Nature
Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2 - Science | AAAS
Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists - Nature
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering - PNAS
Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers - Nature
Trends in kinase drug discovery: targets, indications and inhibitor design - Nature
Robust inference of kinase activity using functional networks - Nature
Kinase drug discovery 20 years after imatinib: progress and future directions - Nature
Magnesium induced structural reorganization in the active site of adenylate kinase - Science | AAAS
Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis - Nature
Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites - Nature
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases - PNAS
Mechanism of activation and autophosphorylation of a histidine kinase - Nature
Kinase drug discovery 20 years after imatinib - Nature
The Protein Kinase Complement of the Human Genome - Science | AAAS
A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains - Nature
Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data - Nature
Research shows why cancer stops responding to kinase-blocking drugs and comes back stronger - U.S. National Science Foundation (.gov)
Targeting cancer with small molecule kinase inhibitors - Nature
Protein Kinase A Is a Master Regulator of Physiological and Pathological Cardiac Hypertrophy - American Heart Association Journals
Tyrosine kinase inhibitors in cancers: Treatment optimization – Part I - ScienceDirect.com
Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective - Nature
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure - New England Journal of Medicine
Cellular functions of the protein kinase ATM and their relevance to human disease - Nature
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein kinase 1 - PNAS
PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase - PNAS
Discovering the first tyrosine kinase - PNAS
Deep learning enables rapid identification of potent DDR1 kinase inhibitors - Nature
The landscape of kinase fusions in cancer - Nature
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology - Nature
An atlas of substrate specificities for the human serine/threonine kinome - Nature
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions - Nature
Discovery of effectors for casein kinase signaling in the African trypanosome | Scientific Reports - Nature
Protein kinase C controls lysosome biogenesis independently of mTORC1 - Nature
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation - Nature
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells - PNAS
Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia - New England Journal of Medicine
Proteome-wide screening for mitogen-activated protein kinase docking motifs and interactors - Science | AAAS
Comprehensive analysis of kinase inhibitor selectivity - Nature
Creation of the first anomeric d/l-sugar kinase by means of directed evolution - PNAS
A dynamically coupled allosteric network underlies binding cooperativity in Src kinase - Nature
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival - Nature
Evidence that phytochrome functions as a protein kinase in plant light signalling - Nature
Revisiting protein kinase–substrate interactions: Toward therapeutic development - Science | AAAS
Targets mapped for almost all human kinase enzymes - Nature
Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling - Science | AAAS
A new autoinhibited kinase conformation reveals a salt-bridge switch in kinase activation - Nature
A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-α signaling - PNAS
Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway - PNAS
Aurora A kinase activation: Different means to different ends - Rockefeller University Press
The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis - Nature
Making New Connections : Role of ERK/MAP Kinase Signaling in Neuronal Plasticity - ScienceDirect.com
Comprehensive characterization of the Published Kinase Inhibitor Set - Nature
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression - PNAS
The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein SOS3 - PNAS
Selective inhibition of the kinase DYRK1A by targeting its folding process - Nature
A chemical switch for inhibitor-sensitive alleles of any protein kinase - Nature
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties - PNAS
Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates - PNAS
The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition - Nature
Kinase mutations in human disease: interpreting genotype–phenotype relationships - Nature
Mechanoenzymatics of titin kinase - PNAS
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit - PNAS
Protein kinases: drug targets for immunological disorders - Nature
Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses - Nature
Ternary structure reveals mechanism of a membrane diacylglycerol kinase - Nature
Rational design of inhibitors that bind to inactive kinase conformations - Nature
Protein Kinase Inhibitors: Insights into Drug Design from Structure - Science | AAAS
Transitions to catalytically inactive conformations in EGFR kinase - PNAS
A calcium sensor – protein kinase signaling module diversified in plants and is retained in all lineages of Bikonta species - Nature
Protein kinase C, an elusive therapeutic target? - Nature
The SYK tyrosine kinase: a crucial player in diverse biological functions - Nature
GTP plus water mimic ATP in the active site of protein kinase CK2 - Nature
Foreign Language Equivalents
Foreign Language Equivalents of 'kinase'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
kinasw,   iknase,   jinase,   kinse,   kiinase,   kinaes,   kinasee,   kinae,   kinnase,   kimase,   kinsse,   kunase,   kiase,   knase,   kinade,   kinsae,   kinas,   kinaase,   linase,   kinasr,   kianse,   kkinase,   kibase,   kniase,   inase,   konase,   kinasse,   kinaae
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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