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kinase
Synonyms
Noun
1. enzyme
Usage
Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing - Nature
Kinase atlas uncovers hidden layers of cell signaling regulation - St. Jude Children's Research Hospital
Type II kinase inhibitors that target Parkinson’s disease–associated LRRK2 - Science | AAAS
Enhancing kinase-inhibitor activity and selectivity prediction through contrastive learning - Nature
The emerging role of kinase fusion proteins in cereal immunity - Nature
AURKA/PHB2 Signaling Fuels Resistance to KRAS G12C Inhibitors - Bioengineer.org
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis - Nature
Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling - Nature
FDA approves 100th small-molecule kinase inhibitor - Nature
Inhibitors supercharge kinase turnover through native proteolytic circuits - Nature
Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway | Communications Biology - Nature
Molecular recording of cellular protein kinase activity with chemical labeling - Nature
Kinase activity of DYRK family members is required for regulating primary cilium length, stability and morphology - Nature
Discovery of effectors for casein kinase signaling in the African trypanosome - Nature
14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state - Nature
Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia - Nature
A novel 5-protein kinase risk signature for predicting glioma prognosis and immunotherapy responsiveness - Nature
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature
Comprehensive evaluation of phosphoproteomic-based kinase activity inference - Nature
A web portal for exploring kinase-substrate interactions | npj Systems Biology and Applications - Nature
Reversible control of kinase signaling through chemical-induced dephosphorylation - Nature
Tandem kinase proteins across the plant kingdom - Nature
Light-gated integrator for highlighting kinase activity in living cells - Nature
Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering - PNAS
A wheat tandem kinase activates an NLR to trigger immunity - Science | AAAS
A bi-kinase module sensitizes and potentiates plant immune signaling - Science | AAAS
Human DNA-dependent protein kinase activation mechanism - Nature
Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N - Nature
Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets - Nature
Kinase drug discovery 20 years after imatinib: progress and future directions - Nature
Trends in kinase drug discovery: targets, indications and inhibitor design - Nature
Aurora A kinase activation: Different means to different ends - Rockefeller University Press
Robust inference of kinase activity using functional networks - Nature
Activation of the essential kinase PDK1 by phosphoinositide-driven trans -autophosphorylation - Nature
Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers - Nature
PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase - PNAS
LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1 - Nature
Mechanism of activation and autophosphorylation of a histidine kinase - Nature
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases - PNAS
Pharmacological approaches to understanding protein kinase signaling networks - Frontiers
Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites - Nature
The Protein Kinase Complement of the Human Genome - Science | AAAS
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein kinase 1 - PNAS
Role of protein kinase PLK1 in the epigenetic maintenance of centromeres - Science | AAAS
Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates - PNAS
Structural and mechanistic insights into mechanoactivation of focal adhesion kinase - PNAS
Targeting cancer with small molecule kinase inhibitors - Nature
Discovering the first tyrosine kinase - PNAS
PKR: A Kinase to Remember - Frontiers
Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter - Nature
Research shows why cancer stops responding to kinase-blocking drugs and comes back stronger - National Science Foundation (.gov)
Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate | Cell Death & Disease - Nature
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease - Nature
Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling - PNAS
Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective - Nature
HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation - Nature
De novo design of tyrosine and serine kinase-driven protein switches - Nature
Kinase drug discovery 20 years after imatinib - Nature
Shutting Down a ‘Dark Kinase’ May Defeat Treatment-Resistant Cancers - Duke University School of Medicine
Inhibitors targeting Bruton’s tyrosine kinase in cancers: drug development advances - Nature
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology - Nature
Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase - Nature
Calibrated geometric deep learning improves kinase–drug binding predictions - Nature
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells - PNAS
A historical overview of protein kinases and their targeted small molecule inhibitors - ScienceDirect.com
The resurrection of RIP kinase 1 as an early cell death checkpoint regulator—a potential target for therapy in the necroptosis era - Nature
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions - Nature
Deep learning enables rapid identification of potent DDR1 kinase inhibitors - Nature
Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix - Nature
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression - PNAS
Activation pathway of Src kinase reveals intermediate states as targets for drug design - Nature
Transitions to catalytically inactive conformations in EGFR kinase - PNAS
Targets mapped for almost all human kinase enzymes - Nature
Regulation of the p21-activated kinase (PAK) by a human Gβ-like WD-repeat protein, hPIP1 - PNAS
Evidence that phytochrome functions as a protein kinase in plant light signalling - Nature
The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis - Nature
A noncanonical sequence phosphorylated by casein kinase 1 in β-catenin may play a role in casein kinase 1 targeting of important signaling proteins - PNAS
Creation of the first anomeric d/l-sugar kinase by means of directed evolution - PNAS
Requirement of protein kinase D1 for pathological cardiac remodeling - PNAS
Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex - Science | AAAS
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP - PNAS
Reversible lysine-targeted probes reveal residence time-based kinase selectivity - Nature
A dynamically coupled allosteric network underlies binding cooperativity in Src kinase - Nature
Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function - PNAS
Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants - PNAS
RedOx regulation of LRRK2 kinase activity by active site cysteines - Nature
Selective inhibition of the kinase DYRK1A by targeting its folding process - Nature
Plant mitogen-activated protein kinase cascades: Negative regulatory roles turn out positive - PNAS
Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway - PNAS
A chemical switch for inhibitor-sensitive alleles of any protein kinase - Nature
Revisiting protein kinase–substrate interactions: Toward therapeutic development - Science | AAAS
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit - PNAS
A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane - PNAS
Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry - Nature
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides - Nature
c-Src protein kinase inhibitors block assembly and maturation of dengue virus - PNAS
New insights into the structural dynamics of the kinase JNK3 - Nature
Comprehensive characterization of the Published Kinase Inhibitor Set - Nature
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties - PNAS
Foreign Language Equivalents
Foreign Language Equivalents of 'kinase'
Language
Equivalent
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Equivalent
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Spanish
Misspellings - Typos
kianse, kinaase, iknase, kinas, kimase, kniase, kunase, knase, linase, kinsae, konase, kinasse, jinase, kinasw, kkinase, kiase, kinaae, kinasr, inase, kinae, kinse, kinade, kinasee, kibase, kiinase, kinnase, kinsse, kinaes
Words Starting with Letter - 'A'
a
a battery
a billion
a bit
a bit much
a capella singing
a cappella singing
a couple of
a few
a fortiori
a good deal
a great deal
a horizon
a hundred
a hundred and one
a hundred thousand
a hundred times
a kempis
a la carte
a la mode
a level
a little
a lot
a million
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