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disulfiram

Synonyms

Noun

1. Antabuse

2. medicine, medication, medicament, medicinal drug

Usage
Disulfiram inhibits Gasdermin D pores formation and improves insulin-dependent glucose uptake and glucose homeostasis in skeletal muscle of obesity-induced insulin-resistant mice | Scientific Reports - Nature
Case Report: Disulfiram-induced optic neuropathy - Frontiers
People are using Ozempic to drink less. We already have FDA-approved drugs for that. - Business Insider
Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine - Nature
Disulfiram inhibits poxvirus extracellular virus production by targeting the palmitoylation sites on F13 - ASM Journals
Two-dimensional MXene nanosheets loaded with disulfiram for multimodal synergistic tumor photothermal-chemodynamic-chemotherapy - ScienceDirect.com
Repurposed alcoholism drug fights liver cancer by targeting fat metabolism and blood supply - EurekAlert!
7 Metronidazole (Flagyl) Interactions to Avoid - GoodRx
Disulfiram inhibits bacterial growth by inducing zinc-dependent reactive oxygen species - Frontiers
Old treatments for AUD are getting a second look. Hope for GLP-1s (Semaglutide ) - Psychology Today
Many patients find disulfiram a "game-changing" Lyme treatment - LymeDisease.org
Effectiveness of Disulfiram as Adjunct to Addiction-Focused Treatment for Persons With Severe Alcohol Use Disorder - Wiley Online Library
Vinegar-Induced Disulfiram Reaction - Psychiatrist.com
Disulfiram-like reaction due to the interaction between vaping and metronidazole: a case report - Nature
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 - Nature
Disulfiram induces redox imbalance and perturbations in central glucose catabolism and metal homeostasis to inhibit the growth of Staphylococcus aureus - Nature
Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism | Communications Biology - Nature
Disulfiram attenuates cell and tissue damage and blood‒brain barrier dysfunction after intracranial haemorrhage by inhibiting the classical pyroptosis pathway - Nature
Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties - Nature
Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion - Nature
​In the 1930s, rubber factory workers drank alcohol and suddenly felt sick. It wasn't just a workplace ill - The Economic Times
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation - Nature
Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism - Nature
Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome - Nature
A key to restoring sight may be held in a drug that treats alcoholism - University of Rochester Medicine
Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis - Nature
Resensitizing multidrug-resistant Gram-negative bacteria to carbapenems and colistin using disulfiram - Nature
Patients can respond very differently to disulfiram. Be cautious. - LymeDisease.org
Antifibrotic effect of disulfiram on bleomycin-induced lung fibrosis in mice and its impact on macrophage infiltration - Nature
Repurposed drug helps obese mice lose weight, improve metabolic function - National Institutes of Health (.gov)
Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115 - Nature
Application of Disulfiram and its Metabolites in Treatment of Inflammatory Disorders - Frontiers
Disulfiram toxicity presenting with peripheral neuropathy and unique lesions on MRI brain. (P5.110) - Neurology® Journals
Are GLP-1s the Best Defense Against Excessive Drinking? - Medscape
Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET - Nature
Imaging phenotype reveals that disulfirams induce protein insolubility in the mitochondrial matrix - Nature
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation - Nature
Impact of Covid-19 pandemic on trajectories of patients with severe alcohol use disorder treated with disulfiram - Nature
A drug repurposing strategy for overcoming human multiple myeloma resistance to standard-of-care treatment - Nature
Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer’s disease hallmarks | Scientific Reports - Nature
Disulfiram--breakthrough drug for Lyme and other tick-borne diseases? - LymeDisease.org
The Disulfiram/Copper Complex Induces Autophagic Cell Death in Colorectal Cancer by Targeting ULK1 - Frontiers
Targeting metabolic vulnerability by combining NAMPT inhibitors and disulfiram for treatment of recurrent ovarian cancer - Nature
An old drug for alcoholism finds new life as cancer treatment - Science | AAAS
Disulfiram downregulates ferredoxin 1 to maintain copper homeostasis and inhibit inflammation in cerebral ischemia/reperfusion injury - Nature
Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative - Nature
Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase - Nature
Disulfiram in glioma: Literature review of drug repurposing - Frontiers
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation - Nature
Disulfiram inhibits inflammatory gatekeeper protein: Could it be helpful in COVID-19? - Boston Children's Answers
Repurposed drug combats obesity in mice - National Institutes of Health (.gov)
Injectable naltrexone tops disulfiram, acamprosate as safer option in alcohol use disorder - Healio
Turning anecdotal irradiation-induced anticancer immune responses into reproducible in situ cancer vaccines via disulfiram/copper-mediated enhanced immunogenic cell death of breast cancer cells - Nature
Inhibition of ALDH2 by disulfiram leads to synthetic lethality via ROS strikes twice in ARID1A-deficient cholangiocarcinoma - ScienceDirect.com
Disulfiram Could Improve Sight in Retinitis Pigmentosa - Review of Optometry
The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency - Frontiers
Use of Disulfiram for Treatment of Alcohol Addiction in Patients With Psychotic Illness - Psychiatry Online
High-capacity glycol chitosan-based nanoemulsion for efficient delivery of disulfiram - ScienceDirect.com
F-FCWAY, Reduces Bone Radioactivity, and Enhances Visualization of Radioligand Binding to Serotonin 5-HT - Journal of Nuclear Medicine
Trial Tests Alcoholism Drug in Relapsed/Refractory Sarcomas to Overcome Chemotherapy Resistance - Cleveland Clinic
Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC - Nature
Alcoholism treatment drug shows potential with COVID-19 - Harvard Gazette
Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2 | Cell Death & Disease - Nature
Disulfiram modulated ROS–MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties | British Journal of Cancer - Nature
Alcohol abuse drug may hold key to treating aggressive childhood brain tumours - The Brain Tumour Charity
How a pioneering doctor uses disulfiram to treat persistent Lyme disease - LymeDisease.org
Antabuse may help revive vision in people with progressive blinding disorders - University of California, Berkeley
Encapsulating Disulfiram: A Promising Path in the Fight Against Obesity - TecScience
Disulfiram-Induced Combined Irreversible Anterior Ischemic Optic Neuropathy and Reversible Peripheral Neuropathy: A Prospective Case Report and Review of the Literature - Psychiatry Online
Alcohol and Metronidazole Interaction: Real or Fake? - Medscape
Old Drug May Have New Trick: Protecting Against COVID-19 Lung Injury - WCM Newsroom
Underused Medication May Be Best Bet for Comorbid AUD and Depression - Psychiatric Times
Pharmacological evaluation of disulfiram analogs as antimicrobial agents and their application as inhibitors of fosB-mediated fosfomycin resistance | The Journal of Antibiotics - Nature
FAIR Health shows Lyme Insurance Claims Made a Huge Jump in the U.S. - LymeDisease.org
Disulfiram inhibits inflammatory gatekeeper protein—could it be helpful in COVID-19? - Medical Xpress
A Drug That Cures Alcoholism May Be the Next Anti-anxiety Medication - Neuroscience News
Existing drug being tested for new use in patients with a rare blinding autoimmune disease - University of Birmingham
The biological activity of bispecific trastuzumab/pertuzumab plant biosimilars may be drastically boosted by disulfiram increasing formaldehyde accumulation in cancer cells - Nature
Alcoholism drug has potential as a COVID-19 treatment, but studies are just getting underway - PhillyVoice
Drug for alcohol use disorder could also treat obesity - Medical News Today
Case Study: New Treatment Options for Patients With Chronic Lymphocytic Leukemia - Pharmacy Times
Disulfiram for Lyme disease: profiles of two patients reporting good outcomes - LymeDisease.org
Copper mixes with alcohol abuse drug for anticancer action - Chemistry World
The Role of Copper in Disulfiram-Induced Toxicity and Radiosensitization of Cancer Cells - Journal of Nuclear Medicine
A patient interviews Dr. Kinderlehrer about disulfiram for Lyme disease - LymeDisease.org
Lyme Times looks at disulfiram--old drug "re-purposed" to treat Lyme disease - LymeDisease.org
Treating Psychiatric Lyme Symptoms with Disulfiram - LymeDisease.org
Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and - Nature
Drug designed to help alcoholics might be the key to treating progressive blindness - Fierce Biotech
Repurposing a Familiar Drug for COVID-19 – May Cut Severe Infection & Reduce Risk of Dying - SciTechDaily
Can a Prescription Help in Your Alcoholism Treatment? - Verywell Mind
Antabuse May Help Revive Vision in People With Progressive Blinding Disorders - University of California, Berkeley
How Mindstrong’s rush to roll out a ‘smoke alarm’ for mental illness led to its downfall - statnews.com
Antabuse May Help Revive Sight in People with Blinding Disorders - Genetic Engineering and Biotechnology News
TOUCHED BY LYME: Treating psychiatric Lyme symptoms with disulfiram - LymeDisease.org
Drugs to treat alcohol addiction are underused - The Economist
I’ve seen first-hand that ECT is a dignified treatment, so why is there still stigma? - The Pharmaceutical Journal
Testing “Shock and Kill” - amfAR, The Foundation for AIDS Research
Transdermal buprenorphine poorly tolerated in people with dementia - The Pharmaceutical Journal
Obese Mice Fed Alcohol Addiction Therapy Shed Weight and Show Improved Metabolic Function - Genetic Engineering and Biotechnology News
Foreign Language Equivalents
Foreign Language Equivalents of 'disulfiram'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
disilfiram,   disulfieam,   disullfiram,   ddisulfiram,   dosulfiram,   disuliram,   disu;firam,   disulfiramm,   isulfiram,   disulfirram,   disulfriam,   disulfiam,   disulfiran,   disulfiraam,   disulfirsm,   disulfram,   disulfuram,   dislfiram,   sisulfiram,   disulffiram,   disulfiiram,   disulgiram,   disuldiram,   diulfiram,   disufliram,   disulfitam,   didulfiram,   disylfiram,   disufiram,   disulfiarm,   diaulfiram,   diisulfiram,   disulifram,   idsulfiram,   dissulfiram,   fisulfiram,   diuslfiram,   dusulfiram,   dsiulfiram,   disulfirma,   dislufiram,   dsulfiram,   disulforam,   disulfira,   disulfirm,   disulfira,,   disukfiram,   disuulfiram
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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