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caspase

Synonyms

Noun

1. protease

2. peptidase, proteinase, proteolytic enzyme

Usage
Caspase 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis - Nature
Caspase-3 cleaves and activates the NADase SARM1 to promote apoptosis, linking two cell death mechanisms - PNAS
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection - Nature
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis - Rockefeller University Press
Discovery of spectosis supports the key role of caspase-8 in determining the type of cell death in mature erythrocytes and erythrocyte death-driven immunogenicity - Nature
Caspase 3 activity is required for skeletal muscle differentiation - PNAS
Caspase-8 comes in from the CYLD - Nature
cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A | Cell Death & Differentiation - Nature
Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution | Oncogene - Nature
Caspase 6 deficiency exacerbates inflammatory bowel disease via enterocyte necroptosis and bacterial translocation - Nature
Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity - Nature
Salidroside ameliorates diabetic amyotrophy by targeting Caspase-3 to inhibit apoptosis - Nature
Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease - Nature
Caspase-2 is a condensate-mediated deubiquitinase in protein quality control - Nature
Caspase-2 protects against ferroptotic cell death - Cell Death & Disease - Nature
Caspases and their substrates - Cell Death & Differentiation - Nature
A long way to go: caspase inhibitors in clinical use - Nature
Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia - Nature
heterodimer enhances complex II assembly and elimination of pancreatic cancer cells - Nature
Caspases as master regulators of programmed cell death: apoptosis, pyroptosis and beyond - Nature
Caspase-7 activates ASM to repair gasdermin and perforin pores - Nature
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death - Nature
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7 - Science | AAAS
The p53-caspase-2 axis in the cell cycle and DNA damage response - Nature
Caspase-1 initiates apoptosis in the absence of gasdermin D - Nature
Drug-induced oxidative stress actively prevents caspase activation and hepatocyte apoptosis - Nature
Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis - Nature
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling - Nature
Regulation of inflammatory processes by caspases - Nature
Apoptosis regulation by subcellular relocation of caspases - Nature
Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease - Nature
Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide - Nature
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells - Science | AAAS
Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation - Nature
Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response - Nature
Caspase involvement in autophagy - Nature
Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth - Nature
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity - Rockefeller University Press
A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death | Scientific Reports - Nature
Arginine methylation of caspase-8 controls life/death decisions in extrinsic apoptotic networks - Nature
Caspase-11 promotes allergic airway inflammation - Nature
Differential roles of caspase-1 and caspase-11 in infection and inflammation - Nature
Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2 - Nature
Evolution of caspase-mediated cell death and differentiation: twins separated at birth - Nature
Identification of Allosteric Inhibitors against Active Caspase-6 - Nature
Ally or traitor: the dual role of p62 in caspase-2 regulation - Cell Death & Disease - Nature
Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies - Nature
Caspase-10: a molecular switch from cell-autonomous apoptosis to communal cell death in response to chemotherapeutic drug treatment - Nature
Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy - PNAS
Caspase-dependent non-apoptotic processes in development - Nature
Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma - Nature
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin - Nature
Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks - PNAS
Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis - Nature
Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion | Cell Death & Differentiation - Nature
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics - Nature
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia - Nature
Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis - Nature
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria - Nature
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth - Nature
Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome - Nature
Caspase-2 Substrates: To Apoptosis, Cell Cycle Control, and Beyond - Frontiers
Old, new and emerging functions of caspases - Cell Death & Differentiation - Nature
Non-lethal roles of the initiator caspase Dronc in Drosophila - Frontiers
Activity of caspase-8 determines plasticity between cell death pathways - Nature
The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities - Nature
The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions | Cell Death & Disease - Nature
Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme - PNAS
Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage - Nature
Inflammatory caspase substrate specificities - ASM Journals
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition - Nature
Neuronal caspase-3 signaling: not only cell death - Nature
Caspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction - Nature
Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis - Nature
Caspase-2: the orphan caspase - Nature
The road to death: Caspases, cleavage, and pores - Science | AAAS
Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment - Nature
Caspase-10 is an initiator caspase in death receptor signaling - PNAS
Exploring caspase-dependent non-lethal cellular processes using Drosophila - Frontiers
Caspase activation pathways: some recent progress - Nature
Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth - PNAS
Caspase-3 cleaves hnRNP K in erythroid differentiation - Nature
Caspase-2-mediated cell death is required for deleting aneuploid cells - Nature
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate - Nature
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function - PNAS
Caspase function in programmed cell death - Nature
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6 - Science | AAAS
Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells - Nature
Dimer formation drives the activation of the cell death protease caspase 9 - PNAS
Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation - Nature
A new type of Caspase-1 upon recognizing bacteria inhibits GSDME-dependent histone modification and NF-κB signaling - Nature
Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity - Nature
Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors - Nature
Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment - Nature
Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis - Nature
New insights into the noncanonical inflammasome point to caspase-4 as a druggable target - Nature
Caspases play in traffic - Nature
Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms - Journal of Neuroscience
Lysosomes, caspase-mediated apoptosis, and cytoplasmic activation of P21, but not cell senescence, participate in a redundant fashion in embryonic morphogenetic cell death - Nature
Functional consequences of caspase activation in cardiac myocytes - PNAS
Foreign Language Equivalents
Foreign Language Equivalents of 'caspase'
Language Equivalent   Language Equivalent
French    Spanish
Misspellings - Typos
ccaspase,   csspase,   casase,   capsase,   casapse,   acspase,   casppase,   caspasr,   cadpase,   caspasse,   caspade,   casoase,   caspsse,   aspase,   casspase,   caspaes,   csapase,   vaspase,   caspas,   cas[ase,   caspasw,   capase,   caspae,   cspase,   caspaase,   xaspase,   caapase,   caaspase,   caspsae,   caspasee,   caspaae,   caspse
Words Starting with Letter - 'A'
a a battery a billion
a bit a bit much a capella singing
a cappella singing a couple of a few
a fortiori a good deal a great deal
a horizon a hundred a hundred and one
a hundred thousand a hundred times a kempis
a la carte a la mode a level
a little a lot a million
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